
What is Considered a High Dose of Zoloft
What is Zoloft and how is it used?
What is considered a high dose of zoloft – Zoloft is a popular prescription medicine used to treat symptoms of mental disorder. It belongs to a class of antidepressants named selective serotonin reuptake inhibitors (SSRIs). Zoloft commonly used to treat Major Depressive disorder, Obsessive-Compulsive Disorder, Panic Disorder, Posttraumatic Stress Disorder (PTSD), Social Anxiety Disorder and Premenstrual Dysphoric Disorder (PMDD).
Each patient or person that used this type of medicine should learn and know what is considered as a high dose of Zoloft, so they won’t have future problems like overdose, or getting side effects from it.
Dosing and Uses
The recommended initial dosage and maximum ZOLOFT dosage in patients with MDD, OCD, PD, PTSD, and SAD are displayed in Table 1 below. A dosage of 25 mg or 50 mg per day is the initial therapeutic dosage, so a higher dose than the indication may called what is considered a high dose of Zoloft.

For adults and pediatric patients, subsequent dosages may be increased in case of an inadequate response in 25 to 50 mg per day increments once a week, depending on tolerability, up to a maximum of 200 mg per day. Given the 24-hour elimination half-life of ZOLOFT, the recommended interval between dose changes is one week.
These are the general regulation on dosing Zoloft :
Dosage Forms Strengths
tablets (Zoloft, generic)
- 25mg
- 50mg
- 100mg
capsules (generic)
- 150mg
- 200mg
oral solution (Zoloft, generic)
- 20mg/mL
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Overdose and Symptoms

If you are taking more than the suggested dose, you might find what is considered a high dose of Zoloft. Each every mental disorder has different indication and regulation. A person’s tolerance for a drug depends on several factors, including age, body weight, overall health, and whether they’ve taken any other substances.
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These variables make it hard to generalize whether a particular amount of Zoloft is potentially harmful. One dose may be exactly right for relieving symptoms for one person, while the same amount of medication could lead to an overdose in another.
Someone who’s taken too much Zoloft could have any one or a combination of many potential reactions. However, there are a few symptoms of Zoloft overdose that are common. There are others that are less common but more severe, with medical consequences.
Too much Zoloft also can also lead to a life-threatening condition called serotonin syndrome, in which dangerously high levels of the neurotransmitter serotonin build up in the brain.2 Symptoms of serotonin syndrome include muscle rigidity, hallucinations, confusion, seizures, and coma. Serotonin syndrome is most likely to happen if another drug that affects serotonin has been taken along with Zoloft.
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Following treatment for a Zoloft overdose, people generally make a full recovery once the drug has fully left their system.3 The next step is to make sure that an overdose does not happen again. If the overdose was accidental, your doctor will advise you on what to do next, which may involve switching to a different antidepressant or adjusting your dosage. If you are having problems in controlling the dose, don’t hesitate to contact us at Rehab Bali for support and assistance from a trained counselor. Or you can come directly to our address at Kubu D’ Lebak Blok II No. 6, Jl. Bedugul, Br. Anyar Kaja, Kec. Kuta Utara, Kab. Badung, Bali, Indonesia 80361